A Note on two unusual cases of Thrombopenic Purpura.

Aquaporin-4 positive neuromyelitis optica spectrum disorders secondary to thrombopenic purpura

RATIONALE Neuromyelitis optica spectrum disorders (NMOSD) is considered as an immune-mediated disorder in the central nervous system (CNS). Numerous autoimmune diseases are frequently complicated with NMOSD and distinct clinical characteristics are noted in NMOSD patients with other autoimmune diseases. However, to our best knowledge, co-occurrence of NMOSD and thrombopenic purpura is rarely id...

A rare case of dermatomyositis associated with immune-complex type glomerulonephritis, idiopathic thrombopenic purpura, pulmonary fibrosis and lung cancer.

Pathological aspects of membranoproliferative glomerulonephritis (MPGN) and haemolytic uraemic syndrome (HUS) / thrombocytic thrombopenic purpura (TTP).

In this paper, epidemiology, pathogenesis and typical morphological aspects of all three types of membranoproliferative glomerulonephritis (MPGN), of the haemolytic uraemic syndrome (HUS) as well as of thrombotic thrombopenic purpura (TTP) will be reviewed on the light microscopical, immunohistological or immunofluorescence and electron microscopical level. In particular, differences in the pat...

Report of two unrelated cases of Familial Thrombotic Thrombocytopeic Purpura

Thrombotic Thrombocytopenic Purpura (TTP) is a rare microangiopathic disorder characterised by the pentad of microangiopathic hemolytic anemia, thrombocytopenic purpura, neurologic abnormalities, fever, and renal disease. Decreased production and/or activity of ADAMTS13 is the cause of this disorder. ADAMTS13 is a metalloproteinase which is responsible of the cleavage of high weight multimers o...

Guillain-barre Syndrome and Idiopathic

To the Editor: We report the case of a 3 year-old girl with Guillain-Barre syndrome and idiopathic thrombocytopenic purpura. She was admitted to the Children's Hospital of Tunis because she suddenly developed, some days after an upper respiratory tract infection, bilateral and symmetric weakness of the lower limbs. During the first week, she suffered from abdominal muscle weakness with moderate...